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T+2 years: A-

A few weeks ago, I had my 2-year follow-up appointment, which consists of the usual blood work and another bone marrow biopsy. Dr. Carroll once again displayed his excellent technique on the biopsy; the initial lidocaine application was really the only painful part. I’m not trying to display some manly image, he’s really quite good at the procedure.

The blood test results showed that my counts are all normal, with the exception of platelets. Those are still hovering just under 100k. Dr. Carroll said that they might never return to the normal range (150-400k), but he’s not concerned since my platelets aren’t dangerously low. There were no surprises on the blood work, since my counts have been pretty stable for a while now. The bone marrow biopsy results, on the other hand, really surprised us! Background: at T+87, the chimerism was 96% donor. At T+180, it was 93.8% donor. At T+365ish, it had dropped to 85% donor. In July 2012, the chimerism dropped again to 76% donor. If you’re not sensing a trend, go back and read the last few lines again. We did not have high expectations for the chimerism results, and even though there had been no evidence of CLL in the previous tests, I was mentally preparing for news that it had come back. Dr. Carroll was his usual stoic, dispassionate self, so we were shocked to hear him say that the chimerism results showed 92.8% donor, with no detectable CLL cells in the microscope or flow cytometry!

Here are a few verses from Romans 8 that seem applicable:

Romans 8:18  I consider that our present sufferings are not worth comparing with the glory that will be revealed in us.

This verse doesn’t mean that I will receive glory because of my suffering over the last 12 years. A wise man once said that context is critical. The first part of Romans 8 tells of the transformative power of the Holy Spirit that enables me to live as a child of God in spite of these circumstances. God’s glory is revealed through how I live my life.

Romans 8:26-28

26 In the same way, the Spirit helps us in our weakness. We do not know what we ought to pray for, but the Spirit himself intercedes for us through wordless groans. 27 And he who searches our hearts knows the mind of the Spirit, because the Spirit intercedes for God’s people in accordance with the will of God. 28 And we know that in all things God works for the good of those who love him, who have been called according to his purpose.

There’s a lot of theology in these three verses. I’ll stick with what I know. Over the past 12 years, there have been many times where I have felt weak, both physically and spiritually. In those times of spiritual weakness, I didn’t know how to pray. I couldn’t find the words to express what I was thinking, but God knew anyway. The “good” in verse 28 is often misinterpreted to mean that God makes all things good. I disagree. I think it means that God will work in good and bad things in our lives to give us some “good” thing, whether that’s a tangible physical good or a spiritual good. In my case, I have plenty of both!

Now that we are this far, we are going to write to my donor to express how thankful we are for her sacrifice. We thought it would be an opportunity for everyone who has been on this journey with us to share their thoughts as well. If you want to do that, you can either write something as a comment or email one of us directly.

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